Droylsden crashed out of the FA Trophy after conceding three bad goals against the visitors from North Yorkshire.
After a last minute equaliser by Pickering on Saturday brought the tie back to the Butchers Arms,the Bloods took the lead after just six minutes when Clive Smith headed home a Shaun Holden corner.
The visitors equalised straight from kick off, with the Droylsden defence appealing for offside,Ryan Blott rounded Thompson to equalise.
Droylsden were in front again six minutes later,Shaun Holden getting to the byline to cross,Sefton Gonzales chesting the ball down and Lewis Doyle drilling the ball into Andrew’s bottom corner.
The visitors should have equalised on twenty five minutes when centre half Niall Tilsley headed against the cross bar from a free kick.
Adam Lund replaced Matty Turnbell for the visitors at half time and in less than the minute they were level when Lewis Taylor played the ball over a static Droylsden defence for Billy Logan to chip Thompson into an empty net.
Lund had a great chance to put the visitors in front shortly after,slicing wide from inside the box before Lewis Taylor was given far too much room with just over half an hour remaining to put the Pikes in front.
Manager Dave Pace made a triple substitution soon after bringing on Liam Dickinson,Phil Marsh and Ollie Ford,but it was the Pikes who nearly made it four when a Billy Logan strike came back off the post.
Droylsden pressed but made little impact on a solid Pickering defence,their best chance a Domaine Rouse header going wide from a corner.